ISO/TS 12025:2012
Nanomaterials — Quantification of nano-object release from powders by generation of aerosols
ISO/TS 12025:2012 provides methodology for the quantification of nano-object release from powders as a result of treatment, ranging from handling to high energy dispersion, by measuring aerosols liberated after a defined aerosolization procedure. In addition to information in terms of mass, the aerosol is characterized for particle concentrations and size distributions.
ISO/TS 12025:2012 provides information on factors to be considered when selecting from the available methods for powder sampling and treatment procedures and specifies minimum requirements for test sample preparation, test protocol development, measuring particle release and reporting data. In order to characterize the full size range of particles generated, the measurement of nano-objects as well as agglomerates and aggregates is recommended in ISO/TS 12025:2012.
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Foreword
Introduction
1 Scope
2 Normative references
3 Terms, definitions and abbreviated terms
3.1 General terms
3.2 Terms related to particle properties and measurement
4 Symbols
5 Factors influencing results of nano-object release from powders
5.1 Test method selection
5.2 Material properties influencing nano-object release from powder
5.3 Test stages
6 Test requirements
6.1 General
6.2 Safety assessment
6.3 Sample preparation
6.4 Sample treatment
6.5 Measurement of aerosolized nano-objects
7 Requirements for test setups and protocols
8 Data reporting
Annex A (informative) Considerations for the selection of the treatment procedure
Annex B (informative) Rotating drum and continuous drop methods
Annex C (informative) Vortex shaker method
Annex D (informative) Dynamic method
Annex E (informative) Disagglomeration principles
Annex F (informative) Selection of the nano-object measuring method
Bibliography
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Foreword
Introduction
1 Scope
2 Normative references
3 Terms, definitions and abbreviated terms
3.1 General terms
3.2 Terms related to particle properties and measurement
4 Symbols
5 Factors influencing results of nano-object release from powders
5.1 Test method selection
5.2 Material properties influencing nano-object release from powder
5.3 Test stages
6 Test requirements
6.1 General
6.2 Safety assessment
6.3 Sample preparation
6.4 Sample treatment
6.5 Measurement of aerosolized nano-objects
7 Requirements for test setups and protocols
8 Data reporting
Annex A (informative) Considerations for the selection of the treatment procedure
Annex B (informative) Rotating drum and continuous drop methods
Annex C (informative) Vortex shaker method
Annex D (informative) Dynamic method
Annex E (informative) Disagglomeration principles
Annex F (informative) Selection of the nano-object measuring method
Bibliography