ISO 23783-3:2022
Automated liquid handling systems — Part 3: Determination, specification and reporting of volumetric performance
This document provides guidance and establishes requirements for collecting and examining volumetric performance data of automated liquid handling systems (ALHS). It specifies how to index and track volumetric performance data and provides descriptive statistics for the evaluation of these data. This document also specifies reporting requirements of ALHS volumetric performance.
This document is applicable to all ALHS with complete, installed liquid handling devices, including tips and other essential parts needed for delivering a specified volume, which perform liquid handling tasks without human intervention into labware.
NOTE For terminology and general requirements of automated liquid handling systems, see ISO 23783-1. Measurement procedures for the determination of volumetric performance are given in ISO 23783-2.
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Foreword
Introduction
1 Scope
2 Normative references
3 Terms and definitions
4 Abbreviated terms
5 Volumetric performance
5.1 General
5.2 Data collection and examination
5.3 Indexing to track data
5.3.1 General
5.3.2 Indexing from the channel perspective
5.3.3 Indexing from the microplate perspective
5.4 Descriptive statistics on an individual channel basis
5.4.1 General
5.4.2 Average volume
5.4.3 Systematic error
5.4.4 Random error
5.5 Descriptive statistics on a run order basis
5.6 Descriptive statistics for entire data sets
5.7 Differences between channels
5.8 Volume increments
6 Reporting
6.1 Reporting of the results
6.1.1 General
6.1.2 Test reports and calibration certificates
6.1.3 Calibration certificates
6.1.4 As-found and as-left reporting
6.1.5 Calibration interval recommendation
Annex A (informative) Applications of descriptive statistics
Bibliography
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Foreword
Introduction
1 Scope
2 Normative references
3 Terms and definitions
4 Abbreviated terms
5 Volumetric performance
5.1 General
5.2 Data collection and examination
5.3 Indexing to track data
5.3.1 General
5.3.2 Indexing from the channel perspective
5.3.3 Indexing from the microplate perspective
5.4 Descriptive statistics on an individual channel basis
5.4.1 General
5.4.2 Average volume
5.4.3 Systematic error
5.4.4 Random error
5.5 Descriptive statistics on a run order basis
5.6 Descriptive statistics for entire data sets
5.7 Differences between channels
5.8 Volume increments
6 Reporting
6.1 Reporting of the results
6.1.1 General
6.1.2 Test reports and calibration certificates
6.1.3 Calibration certificates
6.1.4 As-found and as-left reporting
6.1.5 Calibration interval recommendation
Annex A (informative) Applications of descriptive statistics
Bibliography